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Acomplia (Rimonabant) diet drug is a prescription medicine indicated for obesity, its Active Ingredient is: Rimonabant. Its Manufacturer Approvals: US FDA, WHO, UK MCA. Acomplia (Rimonabant) is an oral-prescription drug which is to be taken once in a day, before breakfast with one full glass of water.
GENERIC XENICAL (Alli) Diet Drug is a prescription medication indicated for weight loss, its Active Ingredient: Orlistat.
Phentermine is a stimulant that is similar to an amphetamine. Phentermine is an appetite suppressant that affects the central nervous system.
Phentermine is used togther with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.
Phentermine may also be used for other purposes not listed in this medication guide.
Important information about phentermine
Taking phentermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take phentermine with any other diet medications without your doctor’s advice.
Phentermine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of this medicine.
Phentermine is only part of a complete program of treatment that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Phentermine may be habit-forming and should be used only by the person it was prescribed for. Never share phentermine with another person, especially someone with a history of drug abuse or addiction. Keep track of the amount of medicine used from each new bottle. Phentermine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. Do not stop using phentermine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using this medicine.
Before taking phentermine
Do not use phentermine if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days. Serious, life threatening side effects can occur if you use phentermine before the MAO inhibitor has cleared from your body.
Taking phentermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take tbis medicine with any other diet medications without your doctor’s advice.
You should not take phentermine if you are allergic to it, or if you have:
- coronary artery disease (hardening of the arteries);
- heart disease;
- severe or uncontrolled high blood pressure;
- overactive thyroid;
- glaucoma;
- if you have a history of drug or alcohol abuse; o
- if you are allergic to other diet pills, amphetamines, stimulants, or cold medications.
If you have any of these other conditions, you may need a phentermine dose adjustment or special tests:
- high blood pressure;
- diabetes; or
- a thyroid disorder.
FDA pregnancy category C. It is not known whether phentermine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Phentermine can pass into breast milk and may harm a nursing baby. You should not breast-feed while taking phentermine. Do not give this medication to a child younger than 16 years old.
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Types of Prescription Weight Loss Drugs
Currently, most available weight loss drugs approved by the FDA are for short-term use, meaning a few weeks or months.
One type of weight-loss medication is “appetite suppressants.” These drugs generally come in the form of tablets or extended-release capsules (pills that release medication over a long period of time). Appetite suppressants can be obtained by a doctor’s prescription or purchased over the counter. One common prescription appetite suppressant is phentermine.
Another type of prescription weight loss drug is a fat absorption inhibitor. Xenical is the only example of this type of treatment approved for use in the U.S. Xenical works by blocking about 30% of dietary fat from being absorbed. Xenical is now sold over-the-counter as Alli.
Xenical is the only weight loss drug approved for longer-term use in significantly obese people, although the safety and effectiveness have not been established for use beyond two years.
Newer drugs are being studied as potential treatments for obesity, some of which are showing promise and may be available in the near future.
How Do Appetite Suppressants Cause Weight Loss?
Appetite suppressants promote weight loss by tricking the body into believing that it is not hungry or that it is full. They decrease appetite by increasing serotonin or catecholamine — two brain chemicals that affect mood and appetite.
How Do Fat Absorption Inhibitors Cause Weight Loss?
Fat absorption inhibitors work by preventing your body from breaking down and absorbing fat eaten with your meals. This unabsorbed fat is eliminated in bowel movements.
Does Xenical Really Work?
In general, Xenical is moderately effective, leading to an average weight loss of 12 to 13 pounds over a one-year period, more than what would be expected with non-drug treatments. Most of the weight loss is generally experienced in the first 6 months.
Over the short term, weight loss from prescription drugs may reduce a number of health risks in obese people. However, there are currently no studies to determine the effects of these medications over the long term.
The Risks of Prescription Weight Loss Drugs
When considering long-term weight loss drugs for obesity, the following possible concerns and risks should be discussed with your doctor:
- Addiction . Currently, all prescription obesity drugs except Xenical are “controlled substances.” This means that doctors are required to follow certain restrictions when prescribing them since they could be addictive.
- Developed tolerance. Most people’s weight tends to level off after six months while taking a weight-loss medication. This leads to a concern that the person has developed a tolerance for the medication. However, it is unclear whether this leveling off is indeed due to a developed tolerance or if the drug has reached its limit in effectiveness.
- Side effects. Most side effects of weight loss drugs are mild (although some can be unpleasant) and usually improve as your body adjusts to the medication. Rarely, serious and even fatal outcomes have been reported.
The Side Effects of Prescription Weight Loss Drugs
Most appetite suppressants are used as a short-term treatment for obese people. Not only do the drugs’ effects tend to wear off after a few weeks, but they can also have some unpleasant side effects, including:
- Increased heart rate
- Increased blood pressure
- Sweating
- Constipation
- Insomnia (inability to sleep or stay asleep)
- Excessive thirst
- Lightheadedness
- Drowsiness
- Stuffy nose
- Headache
- Anxiety
- Dry mouth
Some side effects with Xenical include abdominal cramping, passing gas, leakage of oily stool, increased number of bowel movements, and the inability to control bowel movements. These side effects are generally mild and temporary, but may be worsened by eating foods that are high in fat. Patients should eat a low-fat diet (less than 30% of calories from fat) before starting treatment with Xenical. Because Xenical reduces the absorption of some vitamins, people taking Xenical should take a multivitamin at least two hours before or after taking the medication.
Because these drugs are not recommended for long-term use, it is important for people who are trying to lose weight to learn new eating habits and to exercise while the drug is still effective. Once healthy eating and regular exercise have been learned and established, it is important to continue eating right and exercising if you hope to continue losing weight and keep lost weight from returning.
Weight loss drugs are not for everybody. For example, there are limited studies on these medications’ effects on older adults and on children.
Discussing Prescription Weight Loss Drugs With Your Doctor
Before a doctor will prescribe a prescription weight loss drug, he or she will ask you about the following: any existing allergies you may have, whether or not you are pregnant or breastfeeding, and what types of other drugs you may be taking. Existing medical conditions may also affect the use of these drugs. You should tell your doctor if you have any of the following conditions:
- Diabetes
- High blood pressure
- Heart disease
- Epilepsy (seizures)
- Kidney disease
- Glaucoma
- Alcohol or drug abuse (or a history of)
- Overactive thyroid (hyperthyroidism)
- Depression or other mental illness
- Migraine headaches requiring medication
- Planning to have surgery requiring general anesthesia
- Pregnancy or planning to become pregnant
- Breastfeeding
People who are prescribed appetite suppressants should follow the prescription carefully. Because appetite suppressants may cause drowsiness or lightheadedness, it is important to know how you respond to these medications before you attempt to drive or operate machinery.